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"When in doubt, go to the library."
J.K. Rowling


Evolution of evidence based medicine - EBM

BMJ and JAMA have been at the forefront of publishing and supporting EBM practices. In a recent collaboration they have released a series of videos covering the evolution of EBM practices including commentary on how medicine has been influenced by applying clinical evidence. Interviews with EBM campaigners Muir Gray, Iain Chalmers, & David Sackett can be seen.  

EBP: an oral history.


Double gloves - preventing sharps injuries in healthcare workers

A Cochrane intervention review - based on 34 Randomized Control Trials (RCT) including 6890 person-operations - concluded that percutaneous exposure incidents can be reduced if surgeons and surgical staff wore double gloves.
Source: Cochrane Library

surgical gloves

Seminal fluid markers a more accurate indicator of prostate cancer than standard PSA testing

An Australian study from the Freemasons Foundation Centre for Men's Health at the University of Adelaide indicated RNAs alone was a better predictor of a cancer diagnosis via biopsy than the PSA test.  Lead author Dr Selth said "We also found that the one specific microRNA, miR-200b, could distinguish between men with low grade and higher grade tumours. This is important because, as a potential prognostic tool, it will help to indicate the urgency and type of treatment required."

Source: Endocrine-related cancer:  online first May 2014  - (Full text on request)


Further reading

Screening for prostate cancer - Cochrane intervention review 2013

Screening aims to identify cancers at an early and treatable stage - tests reviewed include the digital rectal examination (DRE), the prostate-specific antigen (PSA) blood test and transrectal ultrasound (TRUS). Authors conclude overdiagnosis and overtreatment are common and are associated with treatment-related harms that need to be communicated to patients.


Management of beta thalassaemia in pregnancy - NICE accredited guideline

Haemoglobinopathies are one of the most common inherited disorders worldwide, and each year there are more than 100 million individuals who are asymptomatic thalassaemia carriers.

Source: RCOG Green-top guideline no.66. March 2014


Print journals received and currently on display

Note:  the links below provide access to the tables of contents, not necessarily the full text.  Full text may be retrieved from the A-Z Journal list (outside of Austin Health you will need your Library barcode no. and PIN)

American journal of cardiology.  Vol. 113, no. 10, 15 May 2014

American journal of medicine.  Vol. 127, no. 6, June 2014

BMJ.  Vol. 248, no. 7959, 24 May 2014

Current problems in diagnostic radiology.  Vol. 43, no. 3, May/June 2014

Infection control & hospital epidemiology.  Vol. 35, no. 6, June 2014

Journal of emergency nursing.  Vol. 40, no. 3, May 2014

Journal of hospital infection.  Vol. 87, no. 1, May 2014

Journal of pediatrics.  Vol. 164, no. 6, June 2014

Journal of the American College of Cardiology.  Vol. 63, no. 18, 13 May 2014; Vol. 63, no. 19, 20 May 2014

Journal of thoracic and cardiovascular surgery.  Vol. 147, no. 6, June 2014

Lancet.  Vol. 383, no. 9932, 31 May 2014

Nature.  Vol. 509, no. 7502, 29 May 2014; Vol. 510, no. 7503, 5 June 2014

New England journal of medicine.  Vol. 370, no. 23, 5 June 2014

Nursing times.  Vol. 110, no. 22, 28 May 2014

Respiratory care.  Vol. 59, no. 3, March 2014; Vol. 59, no. 4, April 2014; Vol. 59, no. 5, May 2014

Seminars in oncology.  Vol. 41, no. 2, April 2014 (Tumor microenvironment); Vol. 41, no. 2, suppl. 3, April 2014 (Paving the way for biosimilars, part 3: clinical and economic impact of oncology biosimilars)

Seminars in oncology nursing.  Vol. 30, no. 2, May 2014 (Personalizing patient care with precision medicine)

Seminars in ultrasound CT and MRI.  Vol. 35, no . 2, April 2014 (Toxic and metabolic encephalopathic syndrome)