ResearchFest scientist

Research

Clinical trials

Researchers at Austin LifeSciences often run clinical trials that need participants from the local community.

All clinical trials conducted at Austin Health are done so under Australian and International guidelines for medical research under the approval of Austin Health Human Research Ethics Committee (HREC).

If you are an Austin LifeSciences researcher and would like to list a trial here, please email a request with a copy of your HREC-approved advertisement to geraldine.richards@austin.org.au

Breathing and Sleep

Participants needed: Healthy 22 - 45 year old patients with untreated Obstructive Sleep Apnoea

The Sleep Research Laboratory at University of Melbourne and the Institute for Breathing and Sleep at Austin Health are recruiting obstructive sleep apnoea patients, 30-45 years old, for a study on memory and mood.

Participation involves a 1.5 hour session at the Sleep Laboratory, where you will be asked to complete some questionnaires and memory tasks.

Participants will be reimbursed for their time. University of Melbourne HREC#1239101.

Enquiries: Melinda Jackson 90356129

 

Cancer Clinical Trials (multiple studies/trials)

Cancer Clinical Trials Centre (CCTC), at Austin Health, is the second largest cancer trials centre in Victoria, and one of the largest in Australia.

There are over 25 consultants actively participating in oncology and haematology clinical trials with a wealth of experience.
The department has specialised experience in Phase 1 to Phase 3 trials across all tumour streams (excluding sarcoma) including complex and first in human trials with a dedicated Phase 1 team.

There are over 250 trials in total with around 25% of these actively recruiting patients at any one time. Please follow the below link to discover what trials are currently open to recruitment: http://trials.cancervic.org.au/

Dementia Research

Are You concerned about your memory or the memory of a loved one?
Do you have a diagnosis of Mild Cognitive Impairment or Alzheimer's disease?

If you answered "Yes" to any of these questions then you may like to get involved in Alzheimer's disease research

Participants may qualify if they are:

  • 50-90yrs old.
  • Have mild Alzheimer's disease or memory problems that may be symptoms of the condition.
  • Have concerns about their memory or have had a family member who has been diagnosed with Alzheimer's disease.
  • Have someone to act as their study partner. This must be someone that knows the participant well and sees them frequently. Who are able to attend appointments and provide accurate information regarding the participants cognitive and functional abilities.
  • Must speak English.

Please contact:

Jenny Kaiser : phone: 9496 2331 email  jenny.kaiser@austin.org.au

Mitra Vazifdar: phone: 9496 2964 email mitra.vazifdar@austin.org.au

MCRU Office: phone 9496 4235

Alternatively you can register you interest by sending an email to: mrcu.recruitment@austin.org.au

Diabetes (five studies/trials)

Trial to treat kidney disease caused by type 2 diabetes

Do you have type 2 diabetes AND kidney disease caused by your diabetes AND are currently on blood pressure medication?

You may be eligible to participate in a clinical research study of a new drug that is being conducted at Austin Health.  The new drug is a tablet taken once a day along with your current medication.
This project has been approved by the Austin Health and St Vincent's Hospital (Melbourne) Human Research Ethics Committee: HREC/15/SVHM/84

For further information see flyer or contact Tamara Debreceni on 9496 4026 or email tamara.debreceni@unimelb.edu.au  

Do you have type 2 diabetes? Do you have problems with your kidneys?

If the answer to both questions is Yes, you may be able to take part in a clinical research study.
The CREDENCETM Study is looking at an investigational (study) medication (taken as a daily capsule) that may help protect the kidneys in people with type 2 diabetes.
We are looking for people who:

• Are 30 years of age or older
• Have a diagnosis of type 2 diabetes
• Have kidney problems related to their diabetes
• Are currently taking medicines to control their kidney problems

If you choose to take part in the CREDENCETM Study, you will be looked after by an experienced study team who will carefully monitor your health and support your diabetes management. You will continue to take your current diabetes medications.

For more information please contact: Jodie Prendergast on 9496 4025 or email:mailto:prenj@unimelb.edu.au

This study has been approved by the Austin Health Human Research Ethics Committee. HREC: 28431754DNE3001

Heart Attack...Stroke.... Are you at risk?

Heart attacks can happen at any time to anyone. It is important to know if you are at risk. There are many factors that increase your chances of having a heart attack including:
• Previous Heart Attack
• Heart Related Disease
• High Cholesterol
• High Blood Pressure
• Diabetes
Local physicians are conducting a research study of an investigational medication and its ability to reduce your risk of having a heart attack and other cardiovascular events such as a stroke. If you are currently taking a medication to lower your cholesterol and have one or more of the conditions listed above, you may qualify for participation in this study. All testing, treatment and parking will be provided free of charge. This project has been approved by the Austin Health and St Vincent's Hospital (Melbourne) Human Research Ethics Committee: HREC 12/SVHM/1.
If interested, please contact Tamara Debreceni on 9496 4026 tamara.debreceni@unimelb.edu.au

Do you have Type 2 Diabetes?

We are testing the effect of an investigational drug on cardiovascular events (heart attack and stroke) in patients with Type 2 Diabetes who may be at risk of these events. If you are male or female aged 50 years or older have Type 2 Diabetes and have never had a heart attack or stroke, you may qualify for a clinical trial. You will be medically supervised. There will be no costs involved. Visits are at the Metabolic Disorders Centre, Austin Health, Heidelberg Repatriation Hospital. This project has been approved by the Austin Health and St Vincent’s Hospital (Melbourne) Human Research Ethics Committee D: HREC D513BC00001.
If interested, please contact Tamara Debreceni on 9496 4026 tamara.debreceni@unimelb.edu.au


Do you want to Lose Weight? Are you Planning Pregnancy in the next 6 months?
If the answer is YES, we want to hear from you!

Researchers are recruiting women aged 18-38 with a BMI>30 who wish to lose weight before planning to become pregnant in the next 6 months. Participants will be placed on a 3 month weight loss plan and will then be observed prior to and during pregnancy. Trial visits are held at the Metabolic Disorders Centre, Austin Health, Heidelberg Repatriation Hospital. All testing, treatment and parking will be provided free of charge. This study has been approved by the Austin Health and Melbourne Health Human Research Ethics Committee: HREC /14/MH/71
To find out more, contact Dr Sarah Price (03) 9496 6221 or sarah.price@unimelb.edu.au OR visit our website www.popstudy.com.au

Endocrinology; Men's Health

The Department of Endocrinology is recruiting people for a drug trial comparing estradiol skin gel and a placebo skin gel (inactive medication).

Potential participants should be receiving androgen deprivation therapy to treat prostate cancer.

Participants in the study will be asked to attend Austin Health four times over a period of six months.

If you are interested and would like further information, please contact Dr Nick Russell on 03 9496 5000.

This study has been approved by the Austin Health Human Research Ethics Committee Reference Number HREC/16/Austin/98.

 

Endocrinology; Transgender research

Transgender research.
Are you about to start gender transition?
Or, are you interested in getting involved as a healthy volunteer?

If you are about to start gender transition with hormone therapy (or a health volunteer not undergoing transition) you may be eligible to take part in a clinical research study. We are studying the changes that occur with hormone therapy on bone, fat, muscle and cardiovascular risk. The study involves questionnaires, bloods tests, and two scans (DXA/body composition and a bone CT).
We are looking for people:
- Age 18 years or older
- About to start gender transition
- Otherwise fit and healthy
- Not previously on gender affirming hormone therapy
- No previously diagnosed bone disease such as osteoporosis
- Willing to attend 5 visits over 2 years
- We are also looking for healthy volunteers (who are not undergoing gender transition)

If you choose to take part, you will be looked after by an experienced study team who will carefully monitor your health. You will continue to take any current medications.

For more information please contact: Dr Ingrid Bretherton on 9496 2486 or email: ibretherton@student.unimelb.edu.au
This study has been approved by the Austin Health Human Research Ethics Committee: HREC17Austin74

 

Kidney Function in Pregnancy Study

The Austin Endocrine Department, in collaboration with the Mercy Hospital for Women, is conducting a study looking at kidney function in pregnancy. 

We are looking for women aged less than 40 who are planning pregnancy or under 12 weeks pregnant. Eligible women will have their kidney function measured prior to (if applicable), during and after pregnancy.

This project has been approved by the Austin Health Human Research Ethics Committee.

If you are interested in participating, please contact Dr Jenny Huynh (Endocrine Fellow) on 03 9496 2260 or j.huynh4@pgrad.unimelb.edu.au for further information.

Postnatal Depression

Internet-based Treatment for Women with Postnatal Depression

The Parent-Infant Research Institute at Austin Health is conducting a study to evaluate a new internet-based treatment program targeted for women experiencing postnatal depression. If you feel you are struggling to cope or experiencing postnatal depression, this program may be of benefit to you.

Each participant receives a phone assessment with a psychologist to discuss treatment options and to link you in with support services.

Participants will be randomly allocated to receive either the Internet-based treatment (MumMoodBooster) program, or routine primary care.

Participants will be asked to complete questionnaires and phone assessments at three time points over three months.

Each participant will be reimbursed for their time completing the questionnaires and for a telephone assessment interview ($35 in total).

The Internet-based treatment is free of charge.

This study has been approved by the Human Research Ethics Committee of Austin Health. For more information and eligibility criteria, contact the Parent-Infant Research Institute on 9496 4496 or piri@austin.org.au.

Post Traumatic Stress Disorder

Do you have PTSD? Have you already tried other treatments?

You may be interested in participating in a clinical trial of a new medication for PTSD called N-acetylcysteine (NAC). NAC is derived from a naturally occurring substance with antioxidant properties.

If you are eligible for the trial, you will be randomly allocated to receive either active NAC or an inactive placebo to take 3 times per day for 12 weeks, while you continue your other treatment as usual. You will be asked to attend 6 appointments at the Psychological Trauma Recovery Service (PTRS) at the Heidelberg Repatriation Hospital in Ivanhoe, where your PTSD symptoms and related difficulties will be assessed by questionnaires and interview.

The research is being conducted by the department of psychiatry at the University of Melbourne and Austin Health. This trial has been approved by the Austin Health Human Research Ethics Committee. HREC/16/Austin/188.

If you are interested in participating, or want to know more, please contact our researcher Anita Dharan : 9496 2624.  Anita.DHARAN2@austin.org.au

Stroke Rehabilitation

Re-imagining Stroke Environments with Virtual Reality (RiSE-VR)

To all Stroke Survivors,

 

 

You are invited to take part in this research project because you have suffered a stroke in the past. The purpose of this research project is to understand the effects of a short exposure to virtual patient room designs on the emotional, cognitive, and physical responses of people with stroke. This is being done to enable us to better design hospital and rehabilitation environments for people recovering from stroke.

1.      Where is the study held?

All investigations will be carried at the Austin Hospital and the Melbourne Brain Centre, Florey Institute of Neuroscience and Mental Health, which is on-site at the Austin Hospital Campus. A parking space will be reserved for you at the Melbourne Brain Centre, Austin Hospital Campus, for each visit.

2.      What is the first step?

Please contact the named researcher (Michelle Shannon) listed below. The researcher can you send you a Participant Information and Consent Form (PICF). This document provides you with more detailed information about the aims of the study and what is involved. If you would like more information about the study, or you are interested in taking part, please telephone or email the study co-ordinators.

Adults who have had a stroke are needed for falls research.

A collaborative study between Austin Health, Melbourne Health and Victoria University investigating a method of improving walking to reduce tripping in people who have had a stroke is currently seeking participants.

You may be eligible to participate if you:

  • have had a first stroke over 6 months ago
  • can walk 50m independently without ankle/foot orthoses 

What will you be asked to do?

  • Participants will be asked to attend five assessment and ten walking training sessions over 5-6 weeks at either Austin Health or Victoria University. 
  • Assessments will be approximately 90 minutes duration, training sessions approximately 60 minutes. 
  • The training sessions involve walking on a treadmill for approximately 10 minutes with light weight markers on your legs to analyse walking.

 

If you feel you might be eligible and are interested in participating, please contact Joanne Quek for further information [phone: 9496 2659 or email: biofeedbstudy@austin.org.au ]

 

This study has been approved by the Austin Health Human Research Ethics Committee Reference Number HREC/15/Austin/516.

 

Weight loss (two studies/trials)

Do you have type 2 diabetes and are you concerned about your weight?

If yes, we are seeking volunteers with type 2 diabetes who are interested in participating in a placebo-controlled weight loss research study of an investigational medication.

 You may qualify for the trial if:

  • You are obese (Body Mass Index between 30-60 kg/m2)
  • You have Type 2 Diabetes
  • You are between 18-65 years of age
  • You must be willing to participate in a 52 week research study involving approximately 12 outpatient visits

For more information or to see if this trial is suitable for you, please contact Research Coordinator, Austin Health, Nicky 9496 2645 or email: ClinicalTrials-UoMrepat@unimelb.edu.au

This research study has been approved by the Austin Health Human Research Ethics Committee (HREC ZAF-203)

 
t4dm Study

Research into Preventing Diabetes Type 2 using Testosterone & Healthy Lifestyle

Free access to Weight Watchers

The Department of Medicine at Austin Health is recruiting men aged 50-74 years, with a waist circumference of 95cm or greater.

Participants would need to be available every 3 months for injection of testosterone or placebo & blood tests.

For further information or to screen yourself for eligibility go to: www.t4dm.org.au click on Join T4DM & complete questionnaire

or contact Jenny Healy on 03 9496 2282 or email t4dm-Austin@unimelb.edu.au

This trial has been approved by the Austin Health Human Research Ethics Committee