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"Coming together is a beginning, staying together is progress, and working together is success"
Henry Ford


Risk of combining medications – Coroner’s reports

"The societal burden of harm from prescribed sedative and analgesic medications now far exceeds that of illicit drugs". The latest Clinical Communique from the Victorian Institute of Forensic Medicine examines the complex issues surrounding the treatment of pain and the risks associated with combining sedative medications.

Source: Clinical Communique 2017; 4(2)

Further reading:
Research has been published exploring whether subscribers to the Clinical Communique (CC) reported clinical practice changes as a result of reading the Communiqué. "Results: 53.0% of respondents reported that their practice had changed after reading the CC. Subscribers also reported that the CC raised awareness (96.5%) and provided ideas about improving patient safety and care (94.1%) leading them to discuss cases with their colleagues (79.6%) and review their practice (75.7%)".
Source: BMJ Open 2017; 7: e014064


Aboriginal people in distress

A Victorian study has explored the issue of help seeking among rural Aboriginal people. It highlights the association between seeking help and suicide or self-harm. "The inability to seek help and share one's traumatic experiences renders an individual less likely to closely connect with others thereby making them more socially isolated. Moreover, social isolation is known to be directly related to suicide particularly among youth".

Source: The Australian Journal of Rural Health 2017; 25: 169-174 

Further reading for NAIDOC week:
Research in Aboriginal communities
"The Picture Talk Project...revealed how much more there is to be learned about how research with remote Aboriginal communities should be conducted such that it is both culturally respectful and, importantly, meaningful for participants".
Source: BMC Medical Ethics 2017; 18: 34 

Deadly Choices empowering Indigenous Australians through social networking sites
"This paper contributes to an understanding of collaborative ways SNSs [social networking sites] can work for health promotion agendas of self-determination and empowerment in an Indigenous Australia context".
Source: Health Promotion International 2017; online first: 5 April


Pregnancy & collaborating with Mother Nature

"The success of tetanus, influenza, and pertussis immunisation during pregnancy has led to consideration of additional maternal immunisation strategies to prevent group B streptococcus and respiratory syncytial virus infections". In this ‘landscape analysis', the authors identify current research priorities including: vaccine responses during pregnancy; transfer of maternal immunity to infants; and interactions between maternal antibodies and infants.

Source: Lancet Infectious Diseases 2017; 17(7): e197-e208


Hospital at home services

There is increasing interest in the potential of ‘early discharge hospital at home' services as a less expensive alternative to inpatient care. This Cochrane review examined the efficacy, costs and benefits of early discharge services, compared to continuing in-hospital care. The review noted that patients receiving care at home might be more satisfied and less likely to be admitted to institutional care, however it found insufficient evidence of economic benefit or improved health outcomes. 

Source: Cochrane Database of Systematic Reviews 2017; 6: CD000356


Family caregiving in oncology

"Family caregivers (FCGs) play a vital role in the direct care and support of patients with cancer... Several studies have demonstrated improved quality of life for family caregivers and improved emotional support from interventions." This review found "strong consensus that FCGs are central to cancer care, and there is an increased interest in developing models of FCG support, which is linked to patient outcomes, with FCGs becoming clinician partners at a time of major shift in oncology to outpatient care".

Source: CA: A cancer journal for clinicians 2017; online first: 20 March


Is there evidence for probiotics?

This study provides a critical overview of the efficacy of probiotics in a wide variety of physiological and pathological conditions from metabolic disease or irritable bowel syndrome, through to depression or hospital infection. The authors note that the only conditions for which the effects of probiotics are considered "evidence based" are antibiotic-associated diarrhoea, Clostridium difficile-associated diarrhoea and respiratory tract infections.

Source: Gut Microbes 2017; online first: 22 June
Full text available for Austin & MHW Heidelberg staff via document delivery


Identifying DVT before metastatic spinal surgery

"Patients requiring surgery for spinal metastases represent a population with unique risks for venous thromboembolism. This study showed a 9.48% incidence of DVT in patients screened preoperatively. The highest rates of preoperative DVT were identified in nonambulatory patients, who were found to have a 4-fold increase in the likelihood of harbouring a DVT. Understanding the preoperative thrombotic status may provide an opportunity for early intervention and risk stratification in this critically ill population".

Source: Journal of Neurosurgery: Spine 2017; online first: 2 June


Austin Health Research Online - recent submissions

Does left ventricular hypertrophy affect cognition and brain structural integrity in type 2 diabetes? Study design and rationale of the Diabetes and Dementia (D2) study
Patel SK, Restrepo C, Werden E, et. al. BMC Endocrine Disorders 2017; 17(1): 24

First episode psychosis moderates the effect of gray matter volume on cognition
Castro-de-Araujo LFS, Kanaan RAA. Psychiatry Research: Neuroimaging 2017; 266: 108-113

The impact of 68Ga-PSMA PET/CT on management intent in prostate cancer: results of an Australian prospective multicenter study
Roach PJ, Francis R, Emmett L, et. al. Journal of Nuclear Medicine 2017; online first: 23 June

18F-Florbetaben PET beta-amyloid binding expressed in Centiloids
Rowe CC, Doré V, Jones G, et. al. European Journal of Nuclear Medicine and Molecular Imaging 2017; online first: 22 June

The performance of flash glucose monitoring in critically ill patients with diabetes
Ancona P, Eastwood GM, Lucchetta L, et. al. Critical Care & Resuscitation 2017 Jun; 19(2): 167-174
Full text available for Austin & MHW Heidelberg staff via document delivery

See more at AHRO, Austin Health Research Online


eBooks Spotlight

Rosen’s emergency medicine : concepts and clinical practice / [edited by] Ron M. Walls, Robert S. Hockberger and Marianne Gausche-Hill – 9th ed. Elsevier, 2018.
This revised edition includes six new chapters and improved organisation to enhance navigation. 

Evidence-based practice in palliative medicine / [edited by] Nathan E. Goldstein and Sean Morrison – Saunders-Elsevier, 2013.
Organised in the form of clinical questions, this book provides evidence related to the key topics encountered during the clinical practice of palliative medicine. 

New books on display
Breastfeeding and human lactation / edited by Karen Wambach and Jan Riordan – 5th ed. Jones & Bartlett Learning, 2016.
This evidence based resource includes topics on workplace related issues, anatomy and biology of lactation, perinatal periods and concern for the mother’s health.


Journals Spotlight

These links provide access to the current table of contents:

Australian Journal of Rural Health

British Journal of Midwifery

Clinical Journal of Pain

Clinical Infectious Diseases

Evidence-Based Medicine



Journal of Medical Ethics


Seminars in Liver Disease

Looking for the latest journal issues?
All our journal titles with electronic access are available via the Journal List
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If you require an article from a journal that is not in the Journal List, please use our online document delivery form.


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