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"To see what is in front of one's nose needs a constant struggle"
George Orwell


Statins to prevent kidney injury in cardiac surgery

Following cardiac surgery the incidence of postoperative acute kidney injury (AKI) is around 30%, with a high risk of postoperative dialysis. Researchers investigated whether preoperative statin treatment can reduce the incidence of AKI. The major findings were: postoperative inflammation was shown to decrease; however preoperative statin treatment did not significantly decrease the incidence of AKI following cardiac surgery nor did it reduce the length of stay rates in ICU or hospital.

Source: Heart, Lung & Circulation 2017; online first: 13 February 
Link to full text is available with ClinicalKey remote access when you are offsite


Managing hyperglycaemia post transplant

The management of hyperglycaemia following kidney transplant is essential to reduce both transplant and diabetes-related complications. This new Cochrane review evaluates the safety and efficacy of glucose-lowering agents to treat pre-existing and new-onset diabetes in kidney transplant recipients. The reviewers conclude that current data is limited and of poor quality and additional randomised controlled trials are required.

Source: The Cochrane Database of Systematic Reviews 2017; 2: CD009966 


Hospital water environment - a reservoir for infections?

Hospitals provide a distinctive environment for bacteria to proliferate and affect critically ill or immunocompromised patients. Carbapenem-resistant organisms in the hospital water environment have been associated with clinical outbreaks in intensive care settings. Although 72% of studies reported controlling outbreaks, only one-third eliminated the organism from the water environment. A combination of interventions from the design of hand-wash basins through to chemical disinfection is required to terminate outbreaks.

Source: Clinical Infectious Diseases 2017; online first 13 February

Further reading

Laboratory-based surveillance of hospital-acquired respiratory virus infection in a tertiary care hospital.
Research indicates that hospital acquired respiratory viral infections are commonly encountered among hospitalised patients, comprising 22.8% from 7,772 laboratory-confirmed cases. The most common viruses were rhinovirus (30.3%), influenza virus (17.6%) and parainfluenza virus (15.6%).
Source: American Journal of Infection Control 2017; online first: 15 February


OT and cancer rehabilitation

The inclusion of occupational therapy (OT) interventions in the rehabilitation of cancer survivors is supported by a new 2-part systematic review. Exercise for cancer-related fatigue and yoga to relieve anxiety and depression, are two of the areas outlined where OT intervention can lead to positive outcomes for survivors.

Source: American Journal of Occupational Therapy 2017; 71: 7102100030p1-7102100030p11 (Part 1) and 7102100040p1-7102100040p8 (Part 2)


Treating melanoma in situ with micrographic surgery

Wide local excision (WLE) is the standard of care for the management of melanoma in situ. The effectiveness of alternative surgical techniques such as Mohs micrographic surgery (MMS) is increasingly being recognised. Research has compared clinical outcomes for both surgery types and concludes that MMS is as effective as WLE. Further studies are required to assess any adverse outcomes, functional differences, or perceived cosmetic differences for patients.

Source: JAMA Dermatology 2017; online first: 22 February 


Did you know?

DynaMed Plus is a point-of-care resource that provides evidence-based information to support clinical care. Mobile access is available with the DynaMed Plus app if downloaded using Austin WiFi. Please consider using your User Preferences in Cerner to put this link into a quick link tab.

This trial has been extended until 17 March - after reviewing DynaMed Plus please complete our survey to provide your input.


Austin Health Research Online - recent submissions

Prevention of hypothermia in patients undergoing orthotopic liver transplantation using the humigard® open surgery humidification system: a prospective randomized pilot and feasibility clinical trial
Weinberg L, Huang A, Alban D, et al. BMC Surgery 2017; 17(1): 10

Efficacy and safety results of ABT-414 in combination with radiation and temozolomide in newly diagnosed glioblastoma
Reardon DA, Lassman AB, van den Bent M, et al. Neuro-Oncology 2016; online first: 30 December

Inhibition of group 1 p21-activated kinases suppresses pancreatic stellate cell activation and increases survival of mice with pancreatic cancer
Yeo D, Phillips P, Baldwin GS, et al. International Journal of Cancer 2017; online first: 7 February

Penile cancer: contemporary lymph node management
O'Brien JS, Perera M, Manning TG, et al. Journal of Urology 2017; online first: 20 January
Link to full text is available with ClinicalKey remote access when you are offsite

Case-control study to investigate variables associated with incidents and adverse events in the emergency department
Hendrie J, Yeoh MJ, Richardson JR, et al. Emergency Medicine Australasia 2017; online first: 24 January

See more at AHRO, Austin Health Research Online


eBooks Spotlight

Atlas of pain management injection techniques / Steven D. Waldman – 4th ed. Elsevier, 2017.
Expanded ultrasound content including illustrations showing correct transducer placement, patient positioning, ultrasound imaging and new injection techniques. Discusses how to evaluate the causes of pain and identify injection site with precision and deliver effective pain relief to patients.

Evidence-based physical diagnosis / Steven McGee – 4th ed. Elsevier, 2018.
Provides clinicians an up-to-date summary of an accurate and traditional physical examination. Each chapter ends with an EBM calculator which rapidly calculates post-test probabilities using the likelihood ratios supplied for each chapter. 

New books on display

Clinical skills for OSCEs / [edited by] Neel Burton and John Lee Allen – 5th ed. Scion, 2015.
Updated and revised by medical students, this edition has every major clinical skill covered in medical school examinations.


Journals spotlight

These links provide access to the current table of contents:


Journal of Child Psychology and Psychiatry

Journal of Gastroenterology & Hepatology

Journal of Infectious Diseases

Melanoma Research


New England Journal of Medicine

Occupational Therapy in Healthcare

Seminars in Fetal & Neonatal Medicine

Transplantation Proceedings

Looking for the latest journal issues?
All our journal titles with electronic access are available via the Journal List
(outside the Austin Health network use your Library barcode no. & PIN for access)

If you require an article from a journal that is not in the Journal List, please use our online document delivery form.


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Sign up now & start using BrowZine - all you need is the free app and a Library card! 


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The Austin Health Sciences Library accepts no liability for the information or advice provided by external links. Links are provided on the basis that readers make their own decisions about the accuracy, currency and reliability of the information contained therein. Any opinions expressed are not necessarily those of Austin Health.