Testing (NATA ISO15189 accredited) is currently offered for the following:
- Therapeutic drugs in plasma/serum: Mycophenolic acid, Perhexiline, Clozapine, Oxypurinol
- Metabolites: plasma total homocysteine
- Hormones/vasoactive agents: catecholamines - adrenaline, noradrenaline and dopamine in plasma and urine
The laboratory has experience with the following (past or developmental) analyses:
- Drugs in plasma/serum: Lignocaine, Verapamil, Fluoxetine, Paroxetine, Amiodarone, Propranalol, Acetaminophen, Minocyclin, numerous chemotherapy agents and many other therapeutic and investigational drugs
- Metabolites: plasma asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA)
- Hormones/vasoactive agents: Endothelin-1, serotonin.
- GFR estimation by measurement of Iohexol clearance.
- Pharmaceutical formulation/stability studies: N-acetylcysteine, Flucloxacillin
The tailored development of customised tests for other agents (new and existing) in biological matrices is also offered, as is support for clinical trials, pharmacokinetic studies and basic research.
Methods used include high pressure liquid chromatography (HPLC), gas chromatography mass spectrometry (GCMS) and radioimmunoassay (RIA).
The laboratory is accredited as a technical unit of Austin Pathology and is closely integrated with the University of Melbourne Department of Medicine. In 2008 the laboratory will be relocating to newly refurbished laboratory facilities on Level 5 of the Lance Townsend Building at Austin Health.
Please contact Andrew Ellis 03 9496 3220 or andrew.ellis@austin.org.au for enquiries.
